![]() ![]() One study found that 16 weeks of 200 μg/day of chromium was able to lower blood sugar and insulin while improving the body’s response to insulin ( 8). Several studies have indicated that taking chromium supplements can improve blood sugar for those with diabetes ( 7, 8). In people with diabetes, there are problems with the body’s normal response to insulin. In healthy people, the hormone insulin has an important role in signaling the body to bring blood sugar into the cells of the body. Chromium picolinate is the form often found in dietary supplements. It plays a role in the metabolism of nutrients through its impact on the hormone insulin. SummaryĬhromium is a mineral found in low doses in many foods. For this reason, this type is commonly found in dietary supplements ( 3, 6).Ĭhromium picolinate is the mineral chromium attached to three molecules of picolinic acid ( 3). However, chromium picolinate is an alternate form of chromium that is absorbed better. Interestingly, the absorption of chromium in the intestines is very low, with less than 2.5% of ingested chromium being absorbed ( 1). Insulin, a molecule released by the pancreas, is important in your body’s processing of carbs, fat and protein ( 5). This safe form, trivalent chromium, is typically considered essential, meaning that it must be obtained from the diet.Īlthough some researchers question whether this mineral is truly essential, it does serve several important functions in the body ( 2).įor example, it is part of a molecule called chromodulin, which helps the hormone insulin perform its actions in the body ( 3, 4). Although one dangerous form can be found in industrial pollution, a safe form is found naturally in many foods ( 1). No one should take more than 300 mcg per day of chromium without the supervision of a doctor.Chromium is a mineral that exists in several forms. 15 Whether these problems were caused by chromium picolinate or, if so, whether other forms of chromium might have the same effects at these high amounts remains unclear. 14 A case of a muscle disease known as rhabdomyolysis appeared in a body builder who took 1200 mcg over 48 hours. 13 A case of anemia, liver dysfunction, and other problems appeared after four to five months of 1,200–2,400 mcg per day. A case of kidney failure appeared after taking 600 mcg per day for six weeks. Three single, unrelated cases of toxicity have been reported from use of chromium picolinate. 12 However, no published evidence supports this assertion. Another source claimed that there have been reports of mild heart rhythm abnormalities with excessive chromium ingestion. 11 However, chromium supplementation was not proven to be the cause of these problems. One report of severe illness (including liver and kidney damage) occurring in a person who was taking 1,000 mcg of chromium per day has been reported. 9 In theory, these changes could increase the risk of cancer, but so far, chromium intake has not been linked to increased incidence of cancer in humans. 7, 8 Chromium picolinate can be altered by antioxidants or hydrogen peroxide in the body to a form that could itself create free radical damage. One study suggested that chromium in very high concentrations in a test tube could cause chromosomal mutations in ovarian cells of hamsters. While there are a few reports of people developing medical problems while taking chromium, a cause-effect relationship was not proven. In supplemental amounts (typically 50–300 mcg per day), chromium has not been found to cause toxicity in humans. ![]()
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See the Submission Guidelines for more detail. Please do not crosspost threads as they will be removed. When posting a screenshot, please include the context (i.e. This obviously does not apply to articles, videos, and pictures - it is intended primarily for social media posts and public comments. All text submissions must be in the form of screenshots or archive.is links. Posts with reddit usernames censored will be removed. This includes non-verified twitter handles, unverified accounts across all other platforms, and license plates. No off-reddit personal information Reddit usernames must be visible. Quality control is at the discretion of the mod team. RulesĪbove all: we only accept submissions about stuff that is lighthearted and uniquely American. Keep in mind that we are here to have a laugh, not to get angry. This is not a place to bring your hatred of Americans or America- we like to keep things friendly and toxic attitudes are not welcome. This is a satire sub to have a laugh at amusing things, from Reddit and beyond, that are uniquely American in nature. Have you recently seen something amusing out of the states? ![]() ![]() ![]() Histologically positive lymph nodes are a determinant factor of lower survival rates in STS, as less than 28.2 months, varying by histology, in the absence of at distance metastasis. In the presence of metastatic disease, the lung is the most common site affected in up to 30%, as a synchronous or metachronous cancer. The Soft-tissue sarcomas (STS) are rare tumors, affecting almost 1% of the population. (D) Immediate postoperative surgical aspect. (B) Tridimensional resection specimen (Soft-tissue sarcoma). (A) Computed tomography of the thigh that demonstrates a soft tissue tumor in medial and adductor compartment. Based on Recist criteria (response evaluation criteria in solid tumours), the patient revealed a partial response and undergone a tridimensional resection surgery in the adductor compartment and a sentinel lymph node dissection at groin topographyįigure 4. A neoadjuvant treatment was realized with three cycles of doxorubicin and ifosfamide, using a dose of 60 mg/m mg/m 2, respectively during the period of February and march of 2020. The main symptom was tight pain and a limited inferior extremity adduction. 40-year-old female patient, Ecog 0 ( eastern cooperative oncology group) with a tumoral mass at the medial topographic site of the right thigh, located at the adductor compartment, with a computed tomography guided biopsy and histopathological examination report of clear cell sarcoma. The follow up was done with physical exam and computer extremity tomography every three months (Figures 1-3).Ĭase 2. The surgery was performed on February 2020 and until November 2020 there were no signs of locoregional recurrence or a distance. Due to the comorbidities and the advanced age, the patient did not receive any adjuvant treatment. ![]() The postoperative report of the pathological examination verified the clear cell sarcoma diagnosis with free surgical margins and sentinel lymph node histologically negative. Through the application of perilesional and intradermal Patent Blue V (1 - 2 mL) with massage in the local area of the lesion for about 5 to 10 minutes, the sentinel lymph node was identified, removed and underwent histological study. A tridimensional resection was done to treat the lesion with free surgical margins, adding the strategy of sentinel lymph node on the left inguinal topography. Due to advanced age and comorbidities, and being a lesion susceptible to adequate surgical margins, the patient underwent surgery. The patient had arterial hypertension and diabetes mellitus. The patient’s main complaint was a mass in the left leg topography with pain and bleeding. 81-year-old female patient, with a soft tissue lesion on the posterior side of the left leg, with a diagnosis of clear cell sarcoma, confirmed by histopathological findings and immunohistochemistry done through the puncture (core biopsy) guided by image examination. All the patients assign an informed consent before the mean procedure authorizing the use of clinical information and imagens by the authors.Ĭase 1. To present two surgically treated clear cell sarcoma cases that have gone through compartmental resection, performed in association with the sentinel lymph node technique. Therefore, the sentinel lymph node (SN) appears as a locoregional staging tool for sarcomas in a more accurate manner, allowing the more radical surgical treatment, appropriate in the search for a better locoregional control taxes and at a distance. Historically, the regional lymph nodes are compromised in some extent between 2% to 7% of sarcomas, raising the risk of involvement according to the histological subtype, like: epithelioid, rhabdomyosarcoma, synovial, angiosarcoma and the clear cell sarcoma. Among the subtypes of soft-tissue sarcoma, CCS is highlighted as one of the tumors that remarkably reach the local lymph nodes very frequently, making it possible to obtain a number up to 40% of histologically positive lymph nodes. Head and neck, in addition to the trunk, are less often affected. Like all the sarcoma tumors, in a great proportion, it tends to affect the extremities. Notably, at the cytogenetic level, it exhibits the presence of a characteristic and reciprocal chromosomal translocation t(12, 22) (q13, q12) resulting in the fusion of the EWS and ATF1 genes. Also called Melanoma of Soft Parts, it can generate, at times, some diagnostic issues when compared to primary cutaneous melanoma. Clear Cell Sarcoma (CCS) represents less than 1% of all sarcomas, which is characterized as a rare and aggressive neoplasm. ![]() ![]() ![]() ![]() This ensures we aren't just running a cycle with a few shirts and a stain strip in there, as underfilling your washer reduces the total scrubbing action present, which affects the results.Īfter running the wash cycles, we let the swatches and laundry dry overnight.įinally, we use a photospectrometer-a device designed to detect changes in color-which allows us determine exactly how much of the stain was removed by each detergent. Once our laundry has been sufficiently dirtied, it's time to clean! All of the detergents are tested using the Maytag MVWC565 top-loading washer on the normal cycle using warm water, using a standardized load of laundry: eight pounds total of pillowcases, towels, and bedsheets. We use dirt, grass, tomato sauce, and fresh red wine in our testing and even dragged a colleague through dirt and grass! We also produce our own stains in addition to the ones that are mechanically created. To ensure testing is consistent, we use mechanically dyed swatches covered in sweat, oil, pig blood, red wine, and cocoa. To simulate the messes you might encounter in the garden or on the soccer field, we uniformly coated white T-shirts with grass and dirt stains. In exchange for having more harsh chemicals than most free-and-clear detergents, you’re getting a superior clean. Persil Sensitive Skin sits on the fence between hypoallergenic laundry detergents and the standard set we’ve been familiar with for years. There is also some concern about prolonged exposure to propylene glycol, which could cause contact dermatitis. Most notable was the usage of sodium borate, also known as borax, which can cause skin irritation. While testing showed that it’s a great cleaner, we did have some concerns about some of the ingredients. Those who like to cook will enjoy that our testing showed Persil did best against red wine and protein stains. We also appreciate the fact that it is formulated to work in cold water. When we popped open the Sensitive Skin bottle, we mercifully found a very mild scent. We prefer the aroma of this version more than the regular ProClean. The results did not surprise us as regular Persil currently holds the No. ![]() Persil ProClean Sensitive Skin came out on top in our cleaning tests for detergents for people with sensitive skin. ![]() ![]() ![]() ![]() In addition, we have to spend time with Edge 2023 and its large infotainment screen before making complex judgments. It also trades physical climate control for those on screen.Ī wrong move, if you ask us, but one might be made (by those less concerned with intuitive climate control) with stunning screen size. Large portrait-style displays are standard across the 2023 Edge model line and replace the 8.0-inch Edge 2020 unit. Maximizing the functionality of infotainment settings is a new giant 12.0-inch touchscreen mounted to the Edge 2023 dashboard. The new color includes two more shades of grey: Carbonized Grey and Lithium Grey. Other updates to Edge 2023 include a new wheel design and several new interior trim options. There are also two new USB ports, including a USB-C port, bringing the total to four. It offers wireless smartphone mirroring capabilities, which means you can connect your phone via Apple CarPlay or Android Auto via wi-fi rather than having to plug it in with a cable. The vertically oriented portrait-style display runs the latest version of Ford’s infotainment software, called Sync 4A, which means improved graphics compared to the old Sync 3 system. The new 12.0-inch display will be standard on every Edge model and even more significant than the optional 10.1-inch unit in the giant Explorer. Note: Some of the dimensions might be different from the exact numbers from the actual manufacturers as they do change with time and also the specific model and configurations.2023 Ford Edge – Ford will probably come with a large touchscreen to the Edge 2023. ![]() Whether you’re in the market for a family vehicle, a daily driver, or a vehicle for weekend adventures, the Ford Edge is definitely worth considering. The Ford Edge also offers a good level of safety features and a towing capacity that can be useful for some buyers. Its exterior dimensions provide a spacious and comfortable cabin for passengers, while its interior dimensions offer ample cargo space for all your needs. The Ford Edge is a versatile and well-rounded SUV that offers a good balance of style, space, and performance. The Edge also offers a towing capacity of up to 3,500 pounds when properly equipped, making it a great option for those who need to tow a small trailer or boat.Īlso see – Ford Escape Dimension Conclusion Safety and Towing The Ford Edge comes with a wide range of standard and optional safety features, including automatic emergency braking, lane-keeping assist, and a rearview camera. The fuel tank capacity is 18.5 gallons for FWD and AWD. The base curb weight of the Edge is 4,122 lbs for 2.0L AWD and 4,515 lbs for 2.7L AWD. Behind the first row, there is 73.4 cubic feet of cargo space, and behind the second row, there is 39.2 cubic feet of cargo space. The Ford Edge can seat up to five passengers and has a passenger volume of 113.9 cubic feet. Dimensionįord Edge Cargo and Passengers Capacities The hip room and shoulder room in both rows are 55.9 inches and 60.3 inches respectively. Legroom in the first row is 42.6 inches, while legroom in the second row is 40.6 inches. The front and rear seats have 40.2 inches and 40.3 inches of headroom, respectively. The 2023 Ford Edge offers ample space for both passengers and cargo. DimensionĪlso see – Ford Explorer Dimension Ford Edge Interior Dimensions These dimensions make the Edge slightly larger than some of its competitors, such as the Honda Passport and the Nissan Murano. The wheelbase, which is the distance between the front and rear wheels, is 112.2 inches. It measures 188.8 inches in length, 75.9 inches in width (without mirrors), and 68.3 inches in height. The 2023 Ford Edge has a sleek and modern design that sets it apart from other midsize SUVs on the market. ![]() ![]() ![]() This setup makes it safe to use, no matter how messy your sex life gets.įurther, the fabric is made specially to open up sex position possibilities. There are two layers of fabric between your bare skin and the Liberator an outer cover and an inner, moisture-resistant liner. The Liberator Combo’s material is body-safe, but the covers are also machine washable, making it a hygienic addition to your closet. I’m not sure what coasters have to do with sex, but I love wordplay! Material And they also sent me four heartfelt green coasters! Heartfelt, as in shaped like a heart but made out of felt. I got a little sample of Uber Lube, one of my favorite lubricants. Lastly, Liberator sent me bonus gifts with my Ramp Wedge Combo, which I always appreciate. One wrong move, and you’ll slice up your lovely little pillow, so don’t be like me: read the instructions before you even open the box! ![]() Eco-compressed packaging is what it’s called, and it’s serious business. If you were smart and read the instructions online or the included instructional pamphlet (like I didn’t! Oops!), you would know not to cut the plastic. ![]() Liberator vacuum-compresses the contents, so when you remove the plastic, it inflates like Violet Beauregarde in Charlie and the Chocolate Factory. However, it’s relatively large, so making it giftable would also probably make this piece of sex furniture unnecessarily expensive.Ī word to the wise: be careful when you open it. The packaging on the Liberator Combo wasn’t extremely giftable-it just came in a discreet cardboard box. Weight: The wedge weighs 2 lbs, and the sex ramp weighs 7.5 lbs.Mechanism: One large and one small sex pillow to support body weight during different positions.Color: Comes in midnight, sapphire, flame, espresso, amethyst, and gray.Material: The cover is nylon microfiber, and the wedge and ramp are polyurethane foam.Liberator Wedge and Ramp Combo features at a glance: View On Lovehoney Design and Features of the Liberator Wedge Ramp Combo Let’s discuss why this Liberator pillow is so life-changing! You don’t have to wait for an injury to realize that a pillow can give you what you need. There comes the point in everyone’s life when they must admit that comfortable sex is good sex. If you don’t think you need sex furniture right now, bookmark this review and read it in 5-10 years. The Liberator is far fancier than just a regular pillow, but it can still ramp up your sex life in a hurry. The Liberator Combo: More Cushion for the Pushin’. ![]() You Can Buy It at the official store for $279 or Lovehoney for $299. It’s also a bit pricey, so if you’re short on cash or unsure if a sex pillow is right for you, I recommend buying an entry-level model, like Liberator Jaz, instead. Who Can Skip It? Acrobats, yoga instructors, and other people who have no trouble with even the most convoluted sexual configurations in the bedroom may not need extra cushion support-although, honestly, I think even they could benefit from additional comfort. It’s a must-have for anyone who wants a super luxurious sex product that offers the perfect angle without much effort. Who Should Try It? If you’re tired of your three-position rut, Liberator Combo can bring back that honeymoon feeling to the relationship. I think it’s well worth the trouble to store, even though it may take up precious real estate in your closet. Overall, it’s a revolutionary sex furniture made for people who want to add something new to their list of favorite positions and take their sex lives from low heat to ultra inferno. It essentially takes an otherwise hard-to-reach G-spot and makes it a bullseye. But in every case, we were more comfortable using the wedge, ramp, or both than having sex flat on the bed. After one month of testing, my partner and I agreed that the Liberator wedge and ramp improved every single position-some by a lot and some by a little. ![]() ![]() ![]() Flashpoint XPLOR 100 Pro - Fitted with OLED. Come and see how I retouch images using the XP Pen Artist 22E Pro pen display, using Photoshop, and for colour grading, the Infinite Color Panel.For years I. ![]() Blood circulation is improved, which reduces any redness, swelling or puffiness of the skin. (Image credit: Shutterstock - blackzheep) The best free photo editors for PC and Mac deliver powerful, professional image editing tools without. With collagen and elastin production sped up, the skin will feel firm and supple. The skin also becomes soft to the touch after treatment. Godox SK400II - Perfect for e-commerce product photography. Red LED light therapy leaves skin feeling healthy, rejuvenated and glowing. Godox MS200 - Adjustable brightness from 5 to 100. Retouch Pro Panel is a cumbersome set of actions - would not touch it with a 10-foot pole. Flashpoint XPLOR 600 - The best strobe light for photography. Not an action and yes, it can be used with smart objects (that's how I use it). This makes me wonder if all/most of their retouching actions could be used with smart objects or if they would require the image to be rasterized. Would also be very interested if anyone has any first hand experience with either of the two plugins and what they are like when used to retouch skin.Įxcelent for skin (even though I use it for any color when necessary for special fx)įrom what I can tell, these plugins look just like a list of actions to use withing PS. They will enhance the lights in your photos just like magic. ![]() I was wondering if anyone could shed some light on what these plugins are like to use and if they are worth it. Does it happen that sometimes you feel like something is missing in your photos but you dont know what it could be These lights and flares will definitely help you. It's excellent when you need a quick, accurate fix. I've never looked into plugins for Photoshop but two different togs recommended I look into the plugin they use ( Portraiture 3 and Retouch Pro Panel ) when they do retouching. ![]() ![]() ![]() Genealogy work has never been more convenient and rewarding. Of course, standard Ancestor Charts, Fan Charts, Descendant Charts, Statistics, Person Reports, Family Reports and several other visualizations can be created and printed with ease.Ĭollect data and enter it in MacFamilyTree on your Mac or MobileFamilyTree on your iPhone, iPod touch or iPad. ![]() Explore your close and not so close relatives and easily spot persons whose history you might want to dig deeper into. MacFamilyTree turns dates, names and facts into informative and impressive reports and diagrams. Get an overview of where you hail from and maybe enthuse your relatives about exploring your family's past at your upcoming family reunion. Be it creating reports, diagrams or browsing your data in the innovative 3D view called Virtual Tree - MacFamilyTree offers a solution for every task. To achieve this, MacFamilyTree 5 has been completely rewritten with the use of the most recent development technique.Īn iPhone/iPod touch client is also available from the Apple AppStore named MobileFamilyTree Watch Demo Video Updates from previous versions are available for $25 (US).Įasily enter and then visualize your family history. These may consist of information about thousands of individuals, including digitized photographic images, sound files and movies. By the use of Apple's revolutionary Core Data technology it is possible to easily sift through huge databases. MacFamilyTree's fifth release offers an entirely new GUI a highly modern, graphical user interface that is individually configurable to your needs. (274 Mb) Software Description Macfamilytree For Windows MacFamilyTree 9 Download and Install for your computer - either Windows PC 10, 8 or 7 and macOS 10 X, 32/64-bit processor, we have you covered. MacFamilyTree is a comprehensive and user-oriented software solution designed from the beginning with one single goal in mind: to help you create a detailed tree of your entire family and to generate genealogy trees spanning entire centuries. MacFamilyTree is one of the few genealogy software built only for Macs and offers. To link this page, insert the following HTML code to your page: ![]() ![]() ![]() As this condition progresses, it causes congestive heart failure. The heart becomes enlarged and flabby, and fluid begins to accumulate in the dog’s lungs. Let us avoid this type of reaction and instead look at the evidence: What do we currently know about the role of diet and taurine in the development of DCM in dogs – and how is it that “grain-free” foods have been recently targeted as a possible dietary cause? Signs of Dilated Cardiomyopathy (DCM) in DogsĭCM is a disease of the heart, which causes the heart muscles themselves to weaken, which, in turn, reduces the ability of the heart to pump blood through the dog’s body as it should. These ingredients are found commonly in foods that are formulated and promoted as “grain-free.”Īs these things go, there followed a lot of hype and a fair bit of hysteria in response. Foods containing high levels of peas, lentils, other legume seeds, and/or potatoes were identified by the FDA as potential risk factors. It is speculated that these cases are related to the consumption of foods that negatively affect taurine status, leading to taurine-deficiency DCM. ![]() The reported cases occurred in breeds that are not considered to be genetically predisposed to this disorder.įurther, a significant number of the dogs were found to have reduced levels of circulating taurine in their blood and have responded positively to taurine supplementation. This disorder is characterized by weakening of the heart muscle, which leads to a decreased ability of the heart to pump, and if untreated, to cardiac failure. Food and Drug Administration (FDA) released an alert to veterinarians and pet owners regarding reports of increased incidence of a heart disease called canine dilated cardiomyopathy (DCM). ![]() Possible Risk Factors for Taurine-Deficiency DCM:įactors that increase taurine-degrading microbes in the intestine ![]() ![]() ![]() You’ll need a 16oz spray bottle for this recipe. This post may contain affiliate links, which means I make a small commission at no extra cost to you. I like to use this spray to get rid of any pesky wasps that wander into our screened porch, then allow the lingering aroma of lemongrass essential oil to deter any other wasps from coming in. According to green pest solutions, dish soap will kill wasps, bees, and hornets. While lemongrass is effective in deterring wasps, both dish soap and lemon juice will effectively kill wasps. Peppermint deters a number of insects, including stinging insects, and works quite well in this recipe. If you are worried about issues with bees, simply use the peppermint combination. It is important to note that lemongrass may attract bees, though when combined with clove, bees have been known to stay away. Now, there are plenty of theories about lemongrass, one is that lemongrass smothers their senses, so they lose coherence and reverse back the way they’ve come for safety. The trouble is, humans! We have food that ‘mimics’ their favorite foods – and our food is easily accessible when we’re sat outside enjoying it, watching the sunset at the same time. What attracts them? They certainly don’t have a negative agenda, much to our feelings about them! What’s more important is to understand why wasps come in the first place. The research into lemongrass isn’t 100% conclusive when it comes to wasps, though… The key to keeping the wasps away is the lemongrass or peppermint. You can even use this spray mid-eating (and it won’t turn you off your food!) ![]() It’s easy to make: Simply combine all ingredients in a spray bottle and shake to mix.You simply spritz it at first sight of the stingy critters, and they’ll head back the way they’ve come (hopefully!) It works! This spray is by far the best solution I’ve found to keep wasps away.In fact, lemongrass effectively deters ants, ticks, and an array of other bugs.īut they do keep a reasonable distance – which is what we want. However, I know that this homemade wasp spray works great for repelling wasps. ![]() I’ve heard that burning coffee granules works, but I haven’t tried this myself… It’s also why Citronella candles and burners fill the shelves of superstores when summer comes around. Lemongrass, in particular, is super offensive to wasps they’ll steer well clear as soon as they sense it. There are options out there, which include electric zappers and fly swatters – we all know about those.īut are you aware that wasps hate certain smells? It’s that all-important question, right?! How to get rid of pesky wasps!! Make it ahead of the season, and I guarantee it’ll have a permanent space on your table – ready to spray when wasps come attacking at a moment’s notice. Why not follow me while I take you through my DIY wasp spray recipe below? So, I figured out how to keep wasps away the natural way. A homemade wasp killer! It’s an essential tool in everyone’s box. Why would I want to use that near myself or my kids, I think? Goodness knows. They smell disgusting and are usually loaded with nasty ingredients labeled with ‘toxic’ in big BOLD letters. Now, there are tons of anti-wasp sprays in stores that you could buy, but they never agreed with my nose. I get so annoyed and frustrated wasps spoil the scene as I run around like a crazy bull eager to escape! The stress that wasps cause is so real. Wasps freak me out big time! Swarming around your drinks bottle, landing in that delicious homemade dessert, and attacking your kids’ sticky fingers. They turn up at the most impromptu time, like an uninvited guest. The flowers bloom, the trees look full and lush, and the air’s fresh and warm. It’s that bitter-sweet something when summertime comes. Want to keep wasps away the natural way? Check out this homemade wasp spray made with fragrant lemongrass and lemon. ![]() |
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